Central Research Themes:

  • Postoperative cognitive dysfunction
  • Pulmonary function in older adults
  • Relationships between cognitive and physical health
  • Longitudinal changes in the  determinants of health
  • Genetic epidemiology cognition and other aging-related processes




1: Enneking FK, Radhakrishnan NS, Berg K, Patel S, Wishin JM, Vasilopoulos T.
Patient-Centered Anesthesia Triage System Predicts ASA Physical Status. Anesth
Analg. 2017 Jun;124(6):1957-1962. doi: 10.1213/ANE.0000000000001712. PubMed PMID:
2: Hester JM, Guin PR, Danek GD, Thomas JR, Titsworth WL, Reed RK, Vasilopoulos
T, Fahy BG. The Economic and Clinical Impact of Sustained Use of a Progressive
Mobility Program in a Neuro-ICU. Crit Care Med. 2017 Jun;45(6):1037-1044. doi:
10.1097/CCM.0000000000002305. PubMed PMID: 28328648.
3: Holroyd JL, Vasilopoulos T (co-first author), Rice MJ, Rand KH, Fahy BG. Incidence of central venous catheter hub contamination. J Crit Care. 2017 Jun;39:162-168. doi:
10.1016/j.jcrc.2017.02.035. Epub 2017 Feb 27. PubMed PMID: 28259730.
4: Mohammad S, Gravenstein N, Gonsalves D, Vasilopoulos T, Lampotang S. Higher
Fresh Gas Flow Rates Decrease Tidal Volume During Pressure Control Ventilation.
Anesth Analg. 2017 May;124(5):1506-1511. doi: 10.1213/ANE.0000000000001944.
PubMed PMID: 28333703.
5: Ju LS, Yang JJ, Gravenstein N, Seubert CN, Morey TE, Sumners C, Vasilopoulos
T, Yang JJ, Martynyuk AE. Role of environmental stressors in determining the
developmental outcome of neonatal anesthesia. Psychoneuroendocrinology. 2017 Apr
7;81:96-104. doi: 10.1016/j.psyneuen.2017.04.001. [Epub ahead of print] PubMed
PMID: 28433802.
6: Xian H, Vasilopoulos T, Liu W, Hauger RL, Jacobson KC, Lyons MJ, Panizzon M,
Reynolds CA, Vuoksimaa E, Kremen WS, Franz CE. Steeper change in body mass across
four decades predicts poorer cardiometabolic outcomes at midlife. Obesity (Silver
Spring). 2017 Apr;25(4):773-780. doi: 10.1002/oby.21791. PubMed PMID: 28349665;
PubMed Central PMCID: PMC5373489.
7: Wasser JG, Vasilopoulos T, Zdziarski LA, Vincent HK. Exercise Benefits for
Chronic Low Back Pain in Overweight and Obese Individuals. PM R. 2017
Feb;9(2):181-192. doi: 10.1016/j.pmrj.2016.06.019. Epub 2016 Jun 23. Review.
PubMed PMID: 27346092.
8: Cole DC, Giordano CR, Vasilopoulos T, Fahy BG. Resident Physicians Improve
Nontechnical Skills When on Operating Room Management and Leadership Rotation.
Anesth Analg. 2017 Jan;124(1):300-307. PubMed PMID: 27918336.
9: Leclerc JL, Lampert AS, Loyola Amador C, Schlakman B, Vasilopoulos T, Svendsen
P, Moestrup SK, Doré S. The absence of the CD163 receptor has distinct temporal
influences on intracerebral hemorrhage outcomes. J Cereb Blood Flow Metab. 2017
Jan 1:271678X17701459. doi: 10.1177/0271678X17701459. [Epub ahead of print]
PubMed PMID: 28358264.
10: Dubose DF, Herman DC, Jones DL, Tillman SM, Clugston JR, Pass A, Hernandez
JA, Vasilopoulos T, Horodyski M, Chmielewski TL. Lower Extremity Stiffness
Changes after Concussion in Collegiate Football Players. Med Sci Sports Exerc.
2017 Jan;49(1):167-172. PubMed PMID: 27501359; PubMed Central PMCID: PMC5161586.
11: Fahy BG, Vasilopoulos T, White P, Culley DJ. Academic Productivity of
Accreditation Council for Graduate Medical Education-Accredited Critical Care
Fellowship Program Directors. Crit Care Med. 2016 Dec;44(12):e1194-e1201. PubMed
PMID: 27495817.
12: Zaremski JL, Galloza J, Sepulveda F, Vasilopoulos T, Micheo W, Herman DC.
Recurrence and return to play after shoulder instability events in young and
adolescent athletes: a systematic review and meta-analysis. Br J Sports Med. 2016
Nov 10. pii: bjsports-2016-096895. doi: 10.1136/bjsports-2016-096895. [Epub ahead
of print] PubMed PMID: 27834676.
13: Chau DF, Vasilopoulos T, Schoepf M, Zhang C, Fahy BG. Syringe Pump
Performance Maintained with IV Filter Use During Low Flow Rate Delivery for
Pediatric Patients. Anesth Analg. 2016 Sep;123(3):705-14. doi:
10.1213/ANE.0000000000001273. PubMed PMID: 27074895.
14: Vincent HK, Vasilopoulos T, Zdziarski LA, Horodyski M, Hagen J, McClelland
JM, Sadasivan KK. Poster 99 Identification of Acute Inpatient Rehabilitation
Targets in Morbidly Obese Trauma Patients. PM R. 2016 Sep;8(9S):S194. doi:
10.1016/j.pmrj.2016.07.142. Epub 2016 Sep 24. PubMed PMID: 27672869.
15: Deatsman S, Vasilopoulos T, Rhoton-Vlasak A. Age and Fertility: A Study on
Patient Awareness. JBRA Assist Reprod. 2016 Aug 1;20(3):99-106. doi:
10.5935/1518-0557.20160024. PubMed PMID: 27584600; PubMed Central PMCID:
16: Evans FM, Mallepally NR, Dubowitz G, Vasilopoulos T, McClain CD, Enneking K.
Factors influencing anesthesia residency selection: impact of global health
opportunities. Can J Anaesth. 2016 Jun;63(6):674-81. doi:
10.1007/s12630-016-0629-7. Epub 2016 Apr 26. PubMed PMID: 27117988.
17: Vasilopoulos T, Morey TE, Dhatariya K, Rice MJ. Limitations of Significance
Testing in Clinical Research: A Review of Multiple Comparison Corrections and
Effect Size Calculations with Correlated Measures. Anesth Analg. 2016
Mar;122(3):825-30. doi: 10.1213/ANE.0000000000001107. Review. PubMed PMID:
18: Panizzon MS, Hauger RL, Sailors M, Lyons MJ, Jacobson KC, Murray McKenzie R,
Rana B, Vasilopoulos T, Vuoksimaa E, Xian H, Kremen WS, Franz CE. A new look at
the genetic and environmental coherence of metabolic syndrome components. Obesity
(Silver Spring). 2015 Dec;23(12):2499-507. doi: 10.1002/oby.21257. Epub 2015 Nov
2. PubMed PMID: 26524476; PubMed Central PMCID: PMC4701648.
19: Przkora R, McGrady W, Vasilopoulos T, Gravenstein N, Solanki D. Evaluation of
the Head-Mounted Display for Ultrasound-Guided Peripheral Nerve Blocks in
Simulated Regional Anesthesia. Pain Med. 2015 Nov;16(11):2192-4. doi:
10.1111/pme.12765. Epub 2015 Apr 30. PubMed PMID: 25930716.
20: Xu C, Tan S, Zhang J, Seubert CN, Gravenstein N, Sumners C, Vasilopoulos T,
Martynyuk AE. Anesthesia with sevoflurane in neonatal rats: Developmental
neuroendocrine abnormalities and alleviating effects of the corticosteroid and
Cl(-) importer antagonists. Psychoneuroendocrinology. 2015 Oct;60:173-81. doi:
10.1016/j.psyneuen.2015.06.016. Epub 2015 Jun 25. PubMed PMID: 26150359; PubMed
Central PMCID: PMC4526322.
21: Vasilopoulos T, Chau DF, Bensalem-Owen M, Cibula JE, Fahy BG. Prior Podcast
Experience Moderates Improvement in Electroencephalography Evaluation After
Educational Podcast Module. Anesth Analg. 2015 Sep;121(3):791-7. doi:
10.1213/ANE.0000000000000681. PubMed PMID: 25839181.
22: Fahy BG, Vasilopoulos T, Ford S, Gravenstein D, Enneking FK. A single consent
for serial anesthetics in burn surgery. Anesth Analg. 2015 Jul;121(1):219-22.
doi: 10.1213/ANE.0000000000000780. PubMed PMID: 25923437.
23: Panizzon MS, Neale MC, Docherty AR, Franz CE, Jacobson KC, Toomey R, Xian H,
Vasilopoulos T, Rana BK, McKenzie R, Lyons MJ, Kremen WS. Genetic and
environmental architecture of changes in episodic memory from middle to late
middle age. Psychol Aging. 2015 Jun;30(2):286-300. doi: 10.1037/pag0000023. Epub
2015 May 4. PubMed PMID: 25938244; PubMed Central PMCID: PMC4451379.
24: Vasilopoulos T, Kremen WS, Grant MD, Panizzon MS, Xian H, Toomey R, Lyons MJ,
Jacobson KC, Franz CE. Individual differences in cognitive ability at age 20
predict pulmonary function 35 years later. J Epidemiol Community Health. 2015
Mar;69(3):261-5. doi: 10.1136/jech-2014-204143. Epub 2014 Oct 1. PubMed PMID:
25273357; PubMed Central PMCID: PMC4756634.
25: Franz CE, Lyons MJ, Spoon KM, Hauger RL, Jacobson KC, Lohr JB, McKenzie R,
Panizzon MS, Thompson WK, Tsuang MT, Vasilopoulos T, Vuoksimaa E, Xian H, Kremen
WS. Post-traumatic stress symptoms and adult attachment: a 24-year longitudinal
study. Am J Geriatr Psychiatry. 2014 Dec;22(12):1603-12. doi:
10.1016/j.jagp.2014.02.003. Epub 2014 Feb 19. PubMed PMID: 24636844; PubMed
Central PMCID: PMC4138283.
26: Vasilopoulos T, Kotwal A, Huisingh-Scheetz MJ, Waite LJ, McClintock MK, Dale
W. Comorbidity and chronic conditions in the National Social Life, Health and
Aging Project (NSHAP), Wave 2. J Gerontol B Psychol Sci Soc Sci. 2014 Nov;69
Suppl 2:S154-65. doi: 10.1093/geronb/gbu025. PubMed PMID: 25360017; PubMed
Central PMCID: PMC4303089.
27: Panizzon MS, Hauger R, Xian H, Vuoksimaa E, Spoon KM, Mendoza SP, Jacobson
KC, Vasilopoulos T, Rana BK, McKenzie R, McCaffery JM, Lyons MJ, Kremen WS, Franz
CE. Interaction of APOE genotype and testosterone on episodic memory in
middle-aged men. Neurobiol Aging. 2014 Jul;35(7):1778.e1-8. doi:
10.1016/j.neurobiolaging.2013.12.025. Epub 2013 Dec 27. PubMed PMID: 24444806;
PubMed Central PMCID: PMC3980008.
28: Rana BK, Dhamija A, Panizzon MS, Spoon KM, Vasilopoulos T, Franz CE, Grant
MD, Jacobson KC, Kim K, Lyons MJ, McCaffery JM, Stein PK, Xian H, O’Connor DT,
Kremen WS. Imputing observed blood pressure for antihypertensive treatment:
impact on population and genetic analyses. Am J Hypertens. 2014 Jun;27(6):828-37.
doi: 10.1093/ajh/hpt271. Epub 2014 Feb 14. PubMed PMID: 24532572; PubMed Central
PMCID: PMC4017930.
29: Kremen WS, Panizzon MS, Franz CE, Spoon KM, Vuoksimaa E, Jacobson KC,
Vasilopoulos T, Xian H, McCaffery JM, Rana BK, Toomey R, McKenzie R, Lyons MJ.
Genetic complexity of episodic memory: a twin approach to studies of aging.
Psychol Aging. 2014 Jun;29(2):404-17. doi: 10.1037/a0035962. PubMed PMID:
24956007; PubMed Central PMCID: PMC4850834.
30: Kremen WS, Jak AJ, Panizzon MS, Spoon KM, Franz CE, Thompson WK, Jacobson KC,
Vasilopoulos T, Vuoksimaa E, Xian H, Toomey R, Lyons MJ. Authors’ response to:
commentary by Johnson et al. Int J Epidemiol. 2014 Apr;43(2):612-3. doi:
10.1093/ije/dyu087. PubMed PMID: 24760875; PubMed Central PMCID: PMC3997381.
31: Kremen WS, Jak AJ, Panizzon MS, Spoon KM, Franz CE, Thompson WK, Jacobson KC,
Vasilopoulos T, Vuoksimaa E, Xian H, Toomey R, Lyons MJ. Early identification and
heritability of mild cognitive impairment. Int J Epidemiol. 2014
Apr;43(2):600-10. doi: 10.1093/ije/dyt242. Epub 2013 Dec 26. PubMed PMID:
24370560; PubMed Central PMCID: PMC3997374.
32: Panizzon MS, Vuoksimaa E, Spoon KM, Jacobson KC, Lyons MJ, Franz CE, Xian H,
Vasilopoulos T, Kremen WS. Genetic and Environmental Influences of General
Cognitive Ability: Is g a valid latent construct? Intelligence. 2014;43:65-76.
PubMed PMID: 24791031; PubMed Central PMCID: PMC4002017.
33: Vasilopoulos T, Grant MD, Franz CE, Panizzon MS, Xian H, Toomey R, Lyons MJ,
Kremen WS, Jacobson KC. Shared and distinct genetic influences among different
measures of pulmonary function. Behav Genet. 2013 Mar;43(2):141-50. doi:
10.1007/s10519-012-9582-6. Epub 2013 Jan 9. PubMed PMID: 23299959; PubMed Central
PMCID: PMC4755302.
34: Jacobson KC, Hoffman CL, Vasilopoulos T, Kremen WS, Panizzon MS, Grant MD,
Lyons MJ, Xian H, Franz CE. Genetic and Environmental Influences on Individual
Differences in Frequency of Play with Pets among Middle-Aged Men: A Behavioral
Genetic Analysis. Anthrozoos. 2012 Dec;25(4):441-456. PubMed PMID: 25580056;
PubMed Central PMCID: PMC4286882.
35: Vasilopoulos T, Franz CE, Panizzon MS, Xian H, Grant MD, Lyons MJ, Toomey R,
Jacobson KC, Kremen WS. Genetic architecture of the Delis-Kaplan Executive
Function System Trail Making Test: evidence for distinct genetic influences on
executive function. Neuropsychology. 2012 Mar;26(2):238-50. doi:
10.1037/a0026768. Epub 2011 Dec 26. PubMed PMID: 22201299; PubMed Central PMCID:
36: Vasilopoulos T, Kremen WS, Kim K, Panizzon MS, Stein PK, Xian H, Grant MD,
Lyons MJ, Toomey R, Eaves LJ, Franz CE, Jacobson KC. Untreated hypertension
decreases heritability of cognition in late middle age. Behav Genet. 2012
Jan;42(1):107-20. doi: 10.1007/s10519-011-9479-9. Epub 2011 Jun 19. PubMed PMID:
21688193; PubMed Central PMCID: PMC3227796.
37: Vasilopoulos T, Mack HA, McClearn GE, Berg S, Johansson B, Vogler GP.
Stability of genetic influences on pulmonary function in a longitudinal study of
octogenarian twins. Am J Hum Biol. 2010 May-Jun;22(3):375-7. doi:
10.1002/ajhb.21003. PubMed PMID: 19844901; PubMed Central PMCID: PMC2854840.
38: Blizard DA, Lionikas A, Vandenbergh DJ, Vasilopoulos T, Gerhard GS, Griffith
JW, Klein LC, Stout JT, Mack HA, Lakoski JM, Larsson L, Spicer JM, Vogler GP,
McClearn GE. Blood pressure and heart rate QTL in mice of the B6/D2 lineage: sex
differences and environmental influences. Physiol Genomics. 2009 Feb
2;36(3):158-66. doi: 10.1152/physiolgenomics.00035.2008. Epub 2008 Dec 9. PubMed
PMID: 19066325; PubMed Central PMCID: PMC2646459.